Product ID:ACCESS TROPONIN I CONTROL, CATALOG NO. 33329
MSDS Date:11/18/1997
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CKMDY

BECKMAN INSTRUMENTS, INC.

1000 LAKE HAZELTINE DRIVE
CHASKA, MN 55318-1084
US

Emergency Phone: (800) 854-3633

Info Phone: (612) 448-4848

Cage: TO606

SANOFI DIAGNOSTICS PASTEUR

CHASKA, MN 55318 US

Telephone: 800-666-7111; 612-448-4848

Cage: 0TEN9

HUMAN SERUM

SUCCINIC ACID (BUTANEDIOIC ACID) C4H6O4

CAS: 110-15-6

RTECS: WM4900000

HUMAN SOURCE MATERIAL (HUMAN TROPONIN I)

SODIUM HYDROXIDE (NAOH)

CAS: 1310-73-2

RTECS: WB4900000

OSHA PEL 2 MG/M3

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

MISC. INORGANIC SALTS (I.E. CACL2)

KATHON (5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE)

CAS: 26172-55-4

RTECS: NX8156850

KATHON (2-METHYL-4-ISOTHIAZOLIN-3-ONE)

CAS: 2682-20-4

RTECS: NX8157080

WATER

CAS: 7732-18-5

RTECS: ZC0110000

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: POTENTIALLY INFECTIOUS MATERIAL
IF SKIN IS PENETRATED AND/OR MUCOUS MEMBRANES ARE EXPOSED. MILD
MUCOUS MEMBRANE AND SKIN IRRITANT. TOXIC CORROSIVE. HARMFUL IF
SWALLOWED, INHALED, OR ABSORBED THROUGH THE SKIN. DESTRUCTIVE TO
TISSUE. CAUSTIC CAPABLE OF CAUSING SEVERE BURNS TO MUCUS
MEMBRANES, THE UPPER RESPIRATORY TRACT, EYES AND SKIN. MAY CAUSE
TEMPORARY EYE, SKIN, AND UPPER RESPIRATO RY TRACT IRRITATION.
CORROSIVE, IRRITANT, POTENTIAL SKIN DESENSITIZER AND IS CONSIDERED
TOXIC IN ITS CONCENTRATED FORM. CHRONIC: NONE PROVIDED BY
MANUFACTURER.
Effects of Overexposure:SYMPTOMS OF OVEREXPOSURE MAY INCLUDE: HEADACHE,
CONGESTION AND EYE IRRITATION. SKIN CONTACT MAY RESULT IN
DERMATITIS.

First Aid:EYE CONTACT: FLUSH EYES WITH COPIOUS AMTS OF WATER FOR AT
LEAST 15 MINS. ENSURE ADEQUATE FLUSHING BY SEPARATING THE EYELIDS
WITH FINGERS. SKIN CONTACT: REMOVE CONTAMINATED CLOTHING. WASH
AND RINSE AFFECTED AREA(S) THOROUGHLY WITH SOAP AND WATER. MAY
CAUSE ALLERGIC SKIN REACTIONS. SWALLOWING: WASH OUT MOUTH WITH
WATER PROVIDED PERSON IS CONCIOUS. INHALATION: REMOVE FROM
EXPOSURE AREA TO FRESH AIR.

Extinguishing Media:WATER, CO2, DRY CHEMICAL OR ALCOHOL FOAM
Fire Fighting Procedures:SELF-CONTAINED BREATHING APPARATUS AND
PROTECTIVE CLOTHING SHOULD BE WORN
Unusual Fire/Explosion Hazard:NOT FLAMMABLE EXCEPT PACKAGING MATERIALS.

Spill Release Procedures:HUMAN BASED MATERIAL SPILLS SHOULD BE TREATED
AS POTENTIALLY INFECTIOUS MATL AND COVERED WITH ABSORBENT MATL,
FOLLOWED BY AN APPLICATION OF APPROP DISINFECTANT. ABSORB, SWEEP
UP SOLIDS, AND PLACE IN A SUITABLE WASTE CONTAINER. BROKEN GLASS
SHOULD BE TREATED AS SHARPS. USE UNIV PRECAUTIONS AND GOOD
CLINICAL LAB PRACTICES. AVOID DIRECT CONTACT W/MATL BY WEARING
APPROP PERSONAL PROTECT EQUIPMENT.

Handling and Storage Precautions:HANDLING: FOLLOW PROPER LAB SAFETY
GUIDELINES FOR HANDLING CHEMICALS AND BIOLOGICALS. WEAR GLOVES TO
PREVENT SKIN CONTACT. AVOID SPLASHING OR GENERATION OF AEROSOLS.
STORAGE: STORE AT 2-10 DEG C.
Other Precautions:COMBUSTION PRODUCTS: NOT FLAMMABLE (EXCEPT PACKAGING
MATERIALS). REACTIVITY: NOT APPLICABLE. REFER TO ASSAY MANUAL
FOR PRODUCT INSERT FOR ADDITIONAL PRODUCT INFORMATION. REFER TO
CHEMICAL SPECIFIC MSDS FOR ADDITIONAL DATA.

Respiratory Protection:A NIOSH APPROVED RESPIRATOR APPROPRIATE FOR THE
EXPOSURE OF CONCERN .
Ventilation:NORMAL LABORATORY VENTILATION IS ADEQUATE UNLESS AEROSOLS
ARE GENERATED. IF AEROSOLS ARE GENERATED, CONSULT WITH YOUR SAFETY
AND ENVIRONMENTAL HEALTH OFFICER.
Protective Gloves:APPROP TO PREVENT SKIN CONTACT. WASH HANDS
THOROUGHLY AFTER REMOVING GLOVES.
Eye Protection:ANSI APPROVED SAFETY GLASSES, GOGGLES OR FACE SHIELD
WITH GLASSES OR GOGGLES.
Other Protective Equipment:LAB COAT OR GOWN TO PREVENT SKIN CONTACT.
EYEWASH & DELUGE SHOWER MEETING ANSI DESIGN CRITERIA .
Work Hygienic Practices:WHEN USING THIS PRODUCT, FOLLOW UNIVERSAL
PRECAUTIONS FOR POTENTIALLY INFECTIOUS MATLS ACCORDING TO THE
CENTERS FOR DISEASE CONTROL (CDC) / NATIONAL INSTITUTES OF HEALTH
(NIH) GUIDELINES AND OSHA REGS.
Supplemental Safety and Health
MATL USED IN THE PREP OF THIS PROD HAS BEEN TESTED AND FOUND
NON-REACTIVE FOR HEPATITS B SURFACE ANTIGEN, ANTIBODIES TO
HEPATITIS C VIRUS, AND HIV-1 AND HIV-2. BECAUSE NO TEST CAN OFFER
COMPLETE ASSU RANCE THAT INFECTIOUS AGENTS ARE ABSENT, HANDLE
MATERIALS AS IF THEY ARE CAPABLE OF TRANSMITTING INFECTIOUS
DISEASE.

pH:5 TO 9
Solubility in Water:REAGENTS SOLUBLE IN WATER
Appearance and Odor:AMBER TO BROWNISH LIQUID (SERUM BASE) IN GLASS
VIALS. NO ODOR.

Stability Indicator/Materials to Avoid:YES
REACTIVITY: NOT APPLICABLE.

Waste Disposal Methods:DISPOSE OF MATERIAL IN ACCORDANCE WITH LOCAL,
STATE, AND FED. REGS. CONTACT YOUR SAFETY AND ENVIRONMENTAL HEALTH
OFFICER FOR DISPOSAL PROCEDURES.

Toxicological Information:KATHON: LD50 = 3350 MG/KG ORAL, RAT; LC50 =
0.33 MG/L/4 HRS (RAT).

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.